Wired - this day in tech: April 16, 1943: Setting the Stage for World’s First Acid Trip

I've always loved the story of how LSD was discovered. It's like a good piece of fiction:
Hofmann, a Swiss chemist, was researching the synthesis of a lysergic acid compound, LSD-25, when he inadvertently absorbed a bit through his fingertips...
From WIRED
Image: Wikipedia
Hofmann's account of the events makes for an entertaining read.

Le Pain Maudit

The Daily Telegraph (UK) reports on claims the CIA conducted clandestine experiments with LSD in small French village in the 1950s. This may have been part of Project MKULTRA (Wikipedia). There are various theories about the poisoning and this seems to be the most colourful.

A 50-year mystery over the 'cursed bread' of Pont-Saint-Esprit, which left residents suffering hallucinations, has been solved after a writer discovered the US had spiked the bread with LSD as part of an experiment.

via Fabius Maximus